Sep 24 2018Cytox, a precision medicine company which today is commercializing polygenic risk scoring (PRS) approaches for assessing genetic risk for developing Alzheimer’s disease (AD) and other neurological diseases, has announced it has expanded its research collaboration with the Australian Imaging, Biomarker & Lifestyle Flagship Study of Ageing (AIBL) to test new algorithms for identifying the pre-symptomatic and mild cognitively impaired people most at risk to progress to AD.Under the expanded agreement Cytox will assess genetic risk for accelerated development of AD using its current, commercially available, research use only approaches developed to run on the Thermo Fisher Scientific Applied Biosystems™ GeneTitan™ Multi-Channel (MC) instrument platform. AIBL will provide biobank samples together with associated longitudinal data from study research participants clinically diagnosed as cognitively normal, with mild cognitive impairment or with AD. Each subject has confirmed amyloid status from PET imaging, with some of the subjects remaining cognitively stable and others cognitively declining during the study period.Related StoriesNew study identifies eight genetic variants associated with anorexia nervosaStudy: Causes of anorexia are likely metabolic and psychologicalHealthy lifestyle lowers dementia risk despite genetic predispositionGenotyping of DNA samples will be performed by Cytox’s validated Australian genotyping services partner, Ramaciotti Centre for Genomics, a national infrastructure facility delivering internationally competitive genomic services and based in Sydney, Australia.”The AIBL biobank presents a tremendous research opportunity due to the number of blood samples from subjects which are extremely well characterized both in terms of cognitive performance and biomarker status over a significant period of time,” states Dr. Richard Pither, CEO of Cytox. “By working closely with AIBL and its researchers, led by AIBL genetic lead, Dr. Simon Laws, we will explore the performance of our PRS approaches for assessing genetic risk for progressing from initial symptoms to fully symptomatic AD.”Through this collaborative work we foresee the data generated will help drug developers running clinical trials and sponsors of large cohort studies better stratify their subjects based on accelerated disease development risk. Over time, and as new treatments for AD make it to market, we plan to make the products and services that result from this collaboration available for routine clinical practice.” Source:http://www.cytoxgroup.com/news/29/94/Cytox-expands-collaboration-with-AIBL-to-identify-those-most-at-risk-to-rapidly-progress-to-Alzheimers.html
Reviewed by Alina Shrourou, B.Sc. (Editor)Oct 3 2018Parkinson’s disease is a neurodegenerative disorder that affects dopamine-producing or dopaminergic neurons. The progressive loss of these neurons is what leads to impairment in movement coordination in those suffering from the illness.Identifying the genes that underlie the loss of these neurons is important to understanding how the disease functions, according to Patrick Cunningham, a PhD student at Lehigh University in Bethlehem, Pennsylvania, where he is investigating the loss of dopaminergic neurons in Drosophila in a model for Parkinson’s disease.Cunningham works in the lab of Daniel T. Babcock, an assistant professor in the Department of Biological Sciences whose research focuses on neuroscience. Among the inquiries that Babcock and his team are focused: Why are certain populations of neurons vulnerable to a particular disease?”So people who have a mutation that might render them vulnerable to Parkinson’s disease tend to lose dopaminergic neurons,” Babcock says. “But why are dopaminergic neurons the ones that are lost? We don’t have an answer for why that is.”In trying to answer this question, Babcock and his team focus on why dopamine-producing neurons selectively die in patients with Parkinson’s disease.The team recently identified the fruit fly protein known as Scarlet as a target gene whose function is required to prevent age-dependent loss of dopaminergic neurons in fruit flies, or Drosophila melanogaster. They found that loss of Scarlet activity causes a progressive loss of dopaminergic neurons, induces locomotor defects, shortens lifespan and functions cell autonomously within dopaminergic neurons. Additionally, they found that this neurodegeneration can be modified by genetically and pharmacologically manipulating levels of metabolites within the kynurenine pathway–a metabolic pathway in cells– and that Scarlet has a neuroprotective role in a model of Parkinson’s disease. These results were recently published and highlighted in The Journal of Cell Science in an article called: “Neurodegeneration and locomotor dysfunction in Drosophila scarlet mutants.”Related StoriesMother calls for protein shake regulation after daughter diesSorting protein in neurons protects against neurodegenerative disordersUMD researchers connect a protein to antibody immunity for the first timeIn an interview for the journal’s “First Person” section, first author Cunningham says: “When I was looking at the rescue experiment to see if Scarlet was neuroprotective in a Parkinson’s disease model I counted the dopaminergic neurons, and, in brain after brain, I saw that they survived.”He adds: “This was amazing to observe, because the experiment demonstrated that Scarlet was sufficient in preventing dopaminergic neuron loss, suggesting a neuroprotective function. Showing the neuroprotective property of Scarlet really stuck with me because it was my first experience that what we do in lab can be directly applied to a disease.”First author Cunningham shares credit with his mentor and senior author, Professor Babcock. In the article, they discuss the discovery’s potential to impact future treatment and prevention of Parkinson’s disease.They write: “Future studies aimed at identifying genes that interact with scarlet, either directly or indirectly, should further aid in understanding why dopaminergic neurons are particularly vulnerable to degeneration. Identifying additional genes that are required to maintain dopaminergic neurons will help further research into therapeutic and preventative treatments for PD patients.” Source:https://www1.lehigh.edu/
Developer’s Problem Riskier Apps If anything, Strafach is understating the problem, maintained Dave Jevans, vice president for mobile security products at Proofpoint.”We’ve analyzed millions of apps and found this is a widespread problem,” he told TechNewsWorld, “and it’s not just iOS. It’s Android, too.”Still, it likely is not yet a cause for great alarm, according to Seth Hardy, director of security research at Appthority.”It’s something to be concerned about, but we’ve never seen it actively exploited in the wild,” he told TechNewsWorld.What the vulnerability does is enable a classic man-in-the-middle attack. Data from the target phone is intercepted before it reaches its destination. It is then decrypted, stored, re-encrypted and then sent to its destination — all without the user’s knowledge.To do that, an app needs to be fooled into thinking it’s communicating with a destination and not an evesdropper.”In order for a man-in-the-middle attack to be successful, the attacker needs a digital certificate that’s either trusted by the application, or the application is not properly vetting the trust relationship,” explained Slawek Ligier, vice president of engineering for security at Barracuda Networks.”In this case, it appears that developers are developing applications in a way that allows any certificate to be accepted,” he told TechNewsWorld. “If the certificate is issued and not expired, they’re accepting it. They’re not checking if it’s been revoked or even if it’s properly signed.” Should Apple act to weed these vulnerable apps from behind its walled garden?”Apple should most certainly remove any of the offending apps from the App Store,” said Sam McLane, head of security engineering at Arctic Wolf.”This is something that is relatively easy to test for and should be enforced by Apple, since the trust model starts with the Apple ecosystem being safe for people to use,” he told TechNewsWorld.Strafach disagreed. “The setup now is exactly as it should be with regards to developer control of networking code,” he said. “Developers can do something about this problem. For affected apps, the fix is only a few lines — less than an hour tops, if that, to fix the matter in affected code.” John Mello is a freelance technology writer and contributor to Chief Security Officer magazine. You can connect with him on Google+. Lazy Coders If Apple tried to address this app vulnerability, it could create headaches for developers, especially those developing enterprise apps, noted Simeon Coney, chief strategy officer for AdaptiveMobile.”A lot of app developers rely on current behaviors to do things like enterprise apps, which may not have a public certificate,” he told TechNewsWorld, “so the responsibility lies more with the app developers to make sure their apps aren’t bundled with this risk.”Apple doesn’t want to force developers to fully trust certificates, added Ligier. “It will break a lot of things, especially internal apps, and generate a lot of unhappy users,” he said.Nevertheless, developers should not release apps that allow for third-party certificates to be blindly accepted, McLane maintained.”This is entirely in their hands to remedy,” he said. “It’s easily tested and only out of laziness would someone ever ship an app that had this egregious security hole in production level code.” Man in the Middle Attack Strafach categorized another 24 iOS apps as “medium risk.” Potentially intercepted information included service login credentials and session authentication tokens for users logged onto the network.Strafach labeled the remaining apps “high risk” because potentially intercepted information included the snatching of financial or medical services login credentials.He did not identify the medium and high risk apps by name, in order to give their makers time to patch the vulnerability in their apps.How concerned should users be about their security when using these apps?”I tried to leave out anything regarding concern level, as I do not want to freak people out too much,” Strafach told TechNewsWorld.”While this is indeed a big concern in my opinion, it can be mostly mitigated by turning off WiFi and using a cellular connection to perform sensitive actions — such as checking bank balances — while in public,” he said. Dozens of applications for Apple’s mobile devices are vulnerable to WiFi snoopers, a security researcher reported this week.Will Strafach, CEO of the Sudo Security Group, identified 76 popular iOS apps available at Apple’s App Store that were vulnerable to wireless eavesdroppers, even though the connections were supposed to be protected by encryption.There have been 18 million downloads of the vulnerable apps, he said.Strafach categorized 33 of the vulnerable apps as “low risk.” Potentially intercepted information included partially sensitive analytics data about a device and partially sensitive personal data, such as an email address or login credentials.VivaVideo, Snap Upload for Snapchat, Volify, Loops Live, Private Browser, Aman Bank, FirstBank, VPN One Click Professional, and AutoLotto: Powerball, MegaMillions Lottery Tickets are some of the apps he assigned to the low-risk category.
Girl Rising Yep, I didn’t really believe this either, but HP, which dominates this industry, has been showing impressive growth in both printers and supplies. This is largely because it rethought them and aggressively moved on opportunities like 3D printing — and this smartphone printer.One of the big surprises was how popular their first Sprocket Printer became. It was primarily a printer for smartphones, which you could carry in your pocket to share pictures you took with your phone immediately.In use, it reminds me a lot of the old Polaroid experience, but without the nasty waiting period or the need to deal with the waste parts of that process. You just send the picture to the printer and in a few seconds, you get a full color picture you can give to your relative or friend as a keepsake, while you keep the digital copy on your phone. The product defines easy set up and use and it is surprisingly popular with millennials, who likely never saw a Polaroid and were expected to go fully digital.There is something about having a picture you can hold in your hands that has transcended generations, however, and created a new category of products. In a way, the Sprocket is HP’s iPod. What I think is particularly interesting is that it largely targets a female audience. In fact, the target demographic is women between the ages of 16 and 24.For instance, rather than the typical male-oriented colors of black, white, gold and silver, the Sprocket 2nd Edition comes in Luna Pearl, Noir, Blush and Lilac.Improvements to this product — which, as you would expect from HP, leads its segment — are sharper colors and higher speed. Some new features, like multi-user functionality and an augmented reality function I haven’t used yet, have received mixed reviews. One cool improvement is that this printer is always on. Earlier versions required you to power up and connect the printer each time you used it.The included app allows you to make basic image fixes like crops, contrast, brightness and color levels. You can add borders and text (make a custom-printed business card, for example). Print price also has dropped from around US$.65 per print to $.45 per print, which is a nice improvement all by itself. The printer itself costs $129.99.What I like the most is that this is one of the few products designed specifically for women that women actually like — it has been surprisingly successful in its earlier iterations. As a result, the new HP Sprocket 2nd Edition is my product of the week. The opinions expressed in this article are those of the author and do not necessarily reflect the views of ECT News Network. HP Sprocket 2nd Edition Photo Printer HP also has provided substantial support to the Girl Rising movement. One of its focuses is to share stories about people who use technology to make the world a better place for girls and women. The idea is that when people learn of the successful programs undertaken by others, they are encouraged that these programs can and do work, and they are motivated to emulate them.This in turn should have a cumulative impact on how people perceive women and open more opportunities to women, and build on the increasing sense that women aren’t standing alone or just being given lip service.HP is standing up and being counted in an effort to do more than complain about the unfairness of it all, and instead to address the unfairness and bring real and measurable change to a world in which female inequality is still very pronounced.Last week, the winners of the Girl Rising Creative Challenge were announced. All are young women working aggressively to change gender inequality in the world. The people are real, the stories are compelling. I was particularly taken by the fact that none of these women are complaining — they are working impressively to drive real change. HP is doing very well this year. Out from under the cloud that smothered it for much of the last decade, with powerful focused leadership and a CEO who has forged an impressive team, the firm arguably is stronger than it has been in decades. Rather than using that strength inappropriately or only to increase revenue, HP has been using part of its strength to make the world a better place, particularly for women.I think that the more we promote and encourage this behavior, the more firms will emulate it, and if this increases in scale, our efforts will improve the world for everyone. HP is one of the firms aggressively going down this path, promising to improve educational opportunities for 100 million students by 2025. This isn’t a trivial number, and education is believed to be one of the core elements holding emerging economies and economically troubled countries back.Lack of education has had an adverse impact on many countries’ gross domestic products, the competence of their governments, and their ability to take care of and protect their populations. Educated people have choices. Education is a force multiplier, making citizens more productive. Learning engages people and keeps them from becoming social problems — or worse, enemy combatants and terrorists.Technology offerings for students affected by the war in Syria allow them to learn how to use the Web more effectively, to help dig out of the mess their country is in so it can return to being viable. This video, narrated by George Clooney, showcases both the scale of the commitment and some of the progress to date. Doing Well by Doing Good We’ve been complaining about inequality for decades, but it is only when people roll up their sleeves and drive change that change happens. These women, heroes all, have done exactly that. Some steps may be larger than others, but every step gradually makes the world a better place for our mothers, daughters, wives and female friends to live. Wrapping Up: Doing Well By Doing Good It’s a recurring theme that we — and by “we” I mean technology analysts and journalists — should give more focus to the activities of firms that are behaving well over the misbehavior of those that are not.People learn by example, and if the only examples all of us — including myself — repeatedly are pounding is that big companies are unethical, do bad things to their customers and environment, and largely are run by *ssh*les, then we’ll promote that bad behavior. Folks will think that everyone else does it, so why shouldn’t they?I think it far better that we focus more on firms that are trying to make the world a better place in order to promote that behavior and actually help make the world a better place. A number of global companies have been busting their humps to do exactly that. The HP Sprocket 2nd Edition, launched last week, is another huge indicator that printers are coming back. For much of this year, technology companies have been showcased in a very poor light.There was the coverage of Facebook’s adverse impact on the 2016 U.S. elections (and other elections worldwide); there was Intel’s security scandal and the firing of its CEO following reports suggestive of insider trading; there was the Google+ breach and coverup; and there have been incidents of nastiness and bullying across all the social networks.As a result, many folks, particularly governments, have been looking at tech firms very unfavorably.Several firms have been moving aggressively to buck this trend, however.Dell has provided substantial funding for pro-women programs led by Karen Quintos.Cisco has made meaningful contributions in cities where it operates, both in responding to disasters and funding programs to uplift the poor.Microsoft has flipped to taking the lead in providing transparency and improving working conditions.HP has undertaken major efforts to address different types of social injustice.HP’s latest effort, in conjunction with the Clooney Foundation for Justice, is a case in point: an impressive initiative to supply and fund schools in places like war-torn Syria.I’ll share my observations on the importance of efforts like these and then close with my product of the week: the Sprocket 2nd Edition, an update to one of my favorite little HP products. HP’s Efforts Rob Enderle has been an ECT News Network columnist since 2003. His areas of interest include AI, autonomous driving, drones, personal technology, emerging technology, regulation, litigation, M&E, and technology in politics. He has an MBA in human resources, marketing and computer science. He is also a certified management accountant. Enderle currently is president and principal analyst of the Enderle Group, a consultancy that serves the technology industry. He formerly served as a senior research fellow at Giga Information Group and Forrester. Email Rob.
Reviewed by James Ives, M.Psych. (Editor)Feb 25 2019UNC School of Medicine researcher Edwin Kim, MD, MS, says the results of a multi-year observational study are encouraging for those suffering from egg allergies.After completing up to four years of egg oral immunotherapy (eOIT) treatment, certain participants were able to safely incorporate egg into their diet for five years. This new research was presented by the study’s first author, Edwin Kim, MD, at the annual American Academy of Allergy, Asthma and Immunology (AAAAI) conference in San Francisco.”Egg allergy is one of the most common food allergies and usually appears in early childhood. It has significant risk for severe allergic reactions and negatively affects quality of life for children with the allergy,” said Kim, assistant professor of medicine and pediatrics at the UNC School of Medicine and director of the UNC Food Allergy Initiative. “While the allergy does seem to go away with age, it can last into the second decade of life for most people. Any treatment that can allow the introduction of egg into the diet of someone with egg allergy provides nutritional benefits and peace of mind for the patient and their family.”UNC School of Medicine was one of five centers to participate in the study, led by the Consortium of Food Allergy Research (COFAR) and funded by the National Institutes of Health (NIH). The trial began with either eOIT or a placebo for 55 patients aged 5-11 who were allergic to egg. The treatments were randomized – 40 participants received eOIT and 15 received the placebo.The treatments lasted up to four years, during which patients were tested for their sensitivity to egg. Those who were considered desensitized – requiring a higher quantity of egg to cause an allergic reaction – could eat 10 grams, or about two teaspoons, of pure egg without reaction. Desensitized patients then stopped eOIT and were tested for sensitivity again. Those who did not have a reaction were considered sustained unresponsiveness (SU). After completing eOIT, concentrated egg (scrambled, fried or boiled egg) and/or baked egg (eggs incorporated into something like a cake) were recommended to be added into the patients’ diet. For five years following the allergy treatment, patients were asked to report how much egg they ate, in what form they ate it, how often they ate it and how they felt afterward.Related StoriesUnreliable diagnostics for fish allergy testingNovel method can help clinicians identify individuals most in need of PrEPScripps CHAVD wins $129 million NIH grant to advance new HIV vaccine approachAt the end of eOIT, 50 percent of patients were classified with SU, 28 percent of patients were classified as desensitized (without SU) and 22 percent as not desensitized. Of SU-classified patients, 100 percent were able to eat both baked and concentrated egg.Desensitized, not desensitized, and placebo groups had more variable ingestion of baked and concentrated egg and had more chance of symptoms from ingestion.”These results further support the effectiveness of eOIT as a safe way of desensitizing children and youth with egg allergy,” said Kim. “Past research also suggests that eating egg may actually shorten the amount of time a patient has the allergy, so any amount of egg that is incorporated into an allergy patient’s diet is helpful.” Source:http://www.med.unc.edu/
Source:https://www.qmul.ac.uk/ Reviewed by Alina Shrourou, B.Sc. (Editor)Mar 19 2019People are likely to choose healthier and more sustainable canteen meals if they are labeled with a traffic light system, according to research from Queen Mary University of London.The study, published in the journal Appetite, also shows that in some cases people were even inclined to choose ‘greener’ meals over ‘healthier’ meals.The researchers looked at the use of traffic lights in a simulated lunchtime canteen set up, for which the colors (red, amber, green) were designed to indicate how environmentally friendly and how healthy the meal options were.The idea being that, when people see the traffic lights associated with different meals, they will opt for the more environmentally friendly options and the healthy options.Previous studies have examined the impact of traffic light systems on consumer choices for individual food products, but this study considered their use in an everyday simulated lunch time set up much like the kinds of situation where people make actual meal choices.This kind of behavioral intervention designed to improve decisions in our day-to-day lives is commonly known as a ‘nudge’.What is novel about this study is that it is able to compare the relative impact of traffic lights, as nudges, to support positive changes in behavior when the traffic lights indicate healthy eating, and when they indicate environmental friendliness.The findings also show that when accompanied with more information about what the traffic lights refer to, such as the actual values of daily calorie intake and acceptable levels of carbon emissions, this then boosted the positive changes towards healthier and more environmentally friendly meals.Dr Magda Osman, lead author of the study from Queen Mary University of London, said: “We show that using traffic light labels on menus influences the meals people choose, and so this simple technique could easily be implemented on menus in bars, cafes, restaurants as well as canteens, to indicate to people the greenness as well as the healthiness of food items.Related StoriesComplement system shown to remove dead cells in retinitis pigmentosa, contradicting previous researchDynamic Light Scattering measurements in concentrated solutionsRetina can restructure itself following gene therapy”In addition, and more importantly, the findings show that the persuasive effects are boosted by general information about daily calorie intakes and acceptable levels of carbon emissions associated with meals. This means, that while traffic light nudges are intuitive to understand, people need additional information to interpret more precisely what the different colors of traffic lights actually refer to.”The study involved seeing pictures of meals available during lunch that participants could choose from where the range of meals were more or less healthy, and more or less environmentally friendly. The experiment compared meal choices when no traffic lights were present, and then when they were present, and looked at the changes in meal choices based on the presence of the traffic lights.Although presenting two traffic lights, one indicating ‘greener’ meals and the other indicating ‘healthier’ meals, at the same time might overload the consumer, the researchers found that presenting both compared to just one actually boosted the positive effect on consumer meal choices.Dr Osman added: “Given the current social policy interests in persuading people to make choices that mean we eat more sustainably, which means eating less red meat, less of depleted fish stocks, and less dairy, and move towards eating more vegetables, then studies like the one we conducted help to show what methods could be used to inform people about sustainable meal options in a clear and intuitive manner.”
The videos being targeted are ones Google packages to advertisers as “preferred” content. While Google has had human reviewers before, it relies heavily on software to flag potential problems. YouTube was criticized for moving too slowly after one of its stars, Logan Paul, posted video of what appears to be a suicide victim.Google said Tuesday evening that it will impose tougher requirements on which video creators can make money from ads.Advertisers don’t want their ads—YouTube’s lifeblood—running next to troubling videos. Last year, Google promised to be more vigilant about stopping terrorist propaganda and extremist content, including using human reviewers. Weird videos aimed at children have also worried advertisers. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Citation: Humans will review video from most popular YouTube creators (2018, January 17) retrieved 18 July 2019 from https://phys.org/news/2018-01-humans-video-popular-youtube-creators.html Google says humans will now review video from its most popular YouTube creators after recent complaints. This Thursday, Jan. 3, 2013, file photo shows Google’s headquarters in Mountain View, Calif. Google says humans will now review video from its most popular YouTube creators after recent complaints. (AP Photo/Marcio Jose Sanchez, File) Explore further YouTube toughens rules regarding which videos get ads © 2018 The Associated Press. All rights reserved.
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Explore further Citation: ‘Smart cane’ could one day help flag gait problems, falling risks more quickly (2018, February 13) retrieved 18 July 2019 from https://phys.org/news/2018-02-smart-cane-day-flag-gait.html A pair of Vanderbilt University engineers have developed an instrumented cane that not only provides added support, but can also analyze your gait to determine your risk of falling. Nilanjan Sarkar, professor of mechanical and computer engineering, says the “IntelliCane” can quantitatively calculate falling risk as accurately as a physical therapist can with their own eyes.If you are a senior citizen, dizziness and balance problems can be a big deal. In the United States, every year one out of three adults over 65 years of age falls and the statistic climbs to one out of two after age 80. Falls can be serious, leading to hip and other bone fractures, brain injury, loss of independence and even death. Falls are also expensive: The cost of treating injuries from falls is estimated at $34 billion annually.The problem is not restricted to the elderly. There are a number of illnesses that cause balance disorders, ranging from ear infections, head injuries and poor blood circulation to Parkinson’s, spinal stenosis and stroke, and these patients could benefit from such a device.”When I realized how big this problem was, we started searching for available solutions,” said Sarkar. “Initially, my thought was to design something to prevent falls, but after more thought and a little experimenting we quickly realized that this was not practical. The next best thing was to determine how to reliably estimate the fall risk so that intervention can be applied when a person’s risk gets so high that they could fall at any time.” Clinical trial examines care strategies for preventing falls at home Credit: Vanderbilt University Currently, physical therapists estimate falling risk by observing the patient walking back and forth between two lines under a variety of conditions—slow and fast, looking right and left, stepping over obstacles, while blindfolded, up and down steps. The therapist then employs a standardized rating scale to evaluate how steady the patient is on each task and combines the ratings into an overall risk estimate.However, this test cannot always capture a patient’s full experience throughout the day, or from day to day, or within their usual environment. Nor can it capture problems the therapist may be unable to see. Sarkar and graduate student Joshua Wade wanted to develop a tool that could help therapists collect much richer data about their patients’ gaits as they went about their everyday lives, enabling therapists to intervene more quickly if needed.Most current research into that area requires patients to place sensors on their body or in their shoes, which the researchers say isn’t ideal. “Body sensors require a significant extra effort on the part of patients. We wanted an approach that was as easy as possible for people to use,” said Wade, who decided to work on the project because of its potential health benefits. “We decided to instrument a cane because it is familiar. Most people with balance problems already use one, and the only thing extra that they have to do is plug it in at night.”The engineers rigged an off-the-shelf offset cane with inertial and force sensors connected to a wireless microcontroller that provides real-time data on how a person uses the cane while walking. The data is fed into an algorithm that analyzes the sensor data and pulls out information about the steadiness of the user’s gait.When they had a design that worked, the engineers tested the system with nine patients. First, they asked the patient to walk around using the IntelliCane. Then they were asked to participate in a standard risk assessment procedure called the Dynamic Gait Index in the presence of a physical therapist, who scored their performance. After analyzing the cane data, the researchers determined that they could predict each patient’s DGI score with a high degree of confidence.”i think it is quite innovative,” said Patricia Fleming, a physical therapist at Vanderbilt University Medical Center who participated in the test. “Many people don’t have access to a sophisticated gait lab, so a device such as this could augment what we do in the clinic. Almost everyone who comes to the neurological clinic where we work has a balance problem and many of them use a cane. So, we think it’s exciting to be part of this project.”Now that the initial study has validated the basic approach, Sarkar and Wade are convinced that it could have a number of benefits. If a person with a balance problem uses the cane regularly, for example, it may be able to detect when its user’s sense of balance begins to deteriorate and report this to his or her doctor. They also think it could be applied to other devices such as wheeled walkers and crutches.With more advanced analysis, the IntelliCane might even be capable of providing detailed enough information to enable doctors to diagnose specific diseases that affect a person’s sense of balance. For example, Parkinson’s might alter a person’s gait in a manner that is detectably different from multiple sclerosis, they speculate.Vanderbilt has applied for a patent on the technology, and Sarkar and Wade have formed a company called Adaptive Technology Consulting to commercialize it. Provided by Vanderbilt University Feeling a little unsteady and don’t know why?
More information: Thomas Alderighi et al, Metamolds, ACM Transactions on Graphics (2018). DOI: 10.1145/3197517.3201381 Provided by Institute of Science and Technology Austria The metamolds (red pieces far left and right) are used to fabricate the silicone molds (greenish and white shapes in the middle). The silicone can then be used repeatedly to form replicas (front). Credit: Luigi Malomo The method of fabricating objects via silicone molding has a long tradition. Until now, however, creating molds for casting complex objects required a lot of experience and involved manual work, which made the process expensive and slow. Researchers from the Istituto di Scienza e Tecnologie dell’Informazione (ISTI-CNR) and the Institute of Science and Technology Austria (IST Austria) have now developed a tool that not only automatically finds the best way of designing the molds, but also delivers templates for so-called “metamolds”: Rigid, 3-D-printed molds used to fabricate the optimized silicone molds. Their method, which can lower the cost of this fabricating technique, is presented at this year’s SIGGRAPH conference. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Citation: Metamolds—molding a mold (2018, August 21) retrieved 18 July 2019 from https://phys.org/news/2018-08-metamoldsmolding-mold.html Explore further When it comes to fabricating a series of identical objects, the technique of molding plays an important role. One of the favored materials for the mold is silicone, as it is deformable, and therefore forgiving when it comes to extracting complex objects at the end of the fabrication process. Extracting the object from the mold generally requires separating the mold pieces without getting them caught in overhanging parts of the object. A careful cut is required to open the mold. This process, which until now involved manual work from an experienced craftsman, has now been automated. “Until now, silicone molding of complex shapes was a craft that needed years of experience and a skillful hand. You needed to know where to place the cuts ideally, and the work was done manually. Our new tool makes this method accessible for everyone,” says Bernd Bickel.The user uploads the desired shape. The tool then calculates where the cuts need to be placed for an optimal result. This means that the smallest possible number of mold pieces is used, and that the object can be safely removed from the mold once it is finished. Then the computer automatically creates the 3-D-printable templates of the metamold, the container that is used to fabricate the ideal silicone mold pieces. The printed metamolds are filled with liquid silicone to produce the final silicone mold pieces, which are reusable, and can be used to cast multiple replicas.The researchers expect that their method will prove useful in jewelry design or art. “When you are not producing millions of copies, this is the method of choice,” says Thomas Alderighi from ISTI-CNR, the first author of the study who has spent two months at IST Austria as an intern in the research group of Bernd Bickel. As noted by Paolo Cignoni, research director at ISTI—CNR, one possible application is the production of a small number of replicas for museums that could be handled by visitors for a deeper experience of the exhibition. The final silicone mold pieces can also be used to create replicas from a variety of materials, including traditional ones like resin, but also unconventional ones like chocolate or ice. Interactive software tool makes complex mold design simple
An iOS 12 mobile operating system that will power new iPhones unveiled on Wednesday, and be pushed out as an update to prior models, has new features to reduce how much they distract people from the real world.Apple senior vice president of software engineering Craig Federighi said of iOS 12 at a developers conference earlier this year the new system offers “detailed information and tools” to help users and parents keep tabs on device use.A new “Screen Time” tool generates activity reports showing how often people pick up their iPhones or iPads, how long they spend in apps or at websites, and numbers of notifications received.Users will be able to set limits on time spent in apps. Parents will be able to get activity reports from their children’s iPhones or iPads, and impose time limits on apps from games and news to social media and messaging.The operating system will also allow people to designate “down time” when iPhones or iPads can’t be used—perhaps a child’s bedtime or a grown-up’s meditation hour.Activist investor Jana Partners and the California State Teachers’ Retirement System (CalSTRS), which both have stakes in Apple, early this year called on the company to give parents more tools to ensure children are using its devices in ways that aren’t hurting them.The investors reasoned that doing so would pose no threat to Apple, because the company makes the bulk of its money selling devices, not from how much people use them.Apple has been working to ramp up revenue from services and digital content such as music and movies, but most of the cash it takes in comes from iPhone sales.The letter cited a growing body of evidence that excessive smartphone use may be having negative consequences on young people.A study of teachers found the vast majority felt smartphones were a growing distraction at schools, eroding the ability of students to focus in class and a seeming cause of social and emotional difficulties. Citation: Updated Apple system takes on smartphone addiction (2018, September 12) retrieved 17 July 2019 from https://phys.org/news/2018-09-apple-smartphone-addiction.html This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Apple’s polished iPhone line-up comes with tools to help users dial back their smartphone obsessions, amid growing concerns over “addiction” and harmful effects on children. Explore further New iPhones unveiled Wednesday will include an updated operating system that helps users and parents keep track of their smartphone use, amid concerns over “addiction” Apple touts privacy features of new operating systems © 2018 AFP
Citation: 5G service rolls out—but not without controversy (2018, October 9) retrieved 17 July 2019 from https://phys.org/news/2018-10-5g-outbut-controversy.html The United States Conference of Mayors called the ruling “an unprecedented federal intrusion into local (and state) government property rights that will have substantial and continuing adverse impacts on cities and their taxpayers, including reduced funding for essential local government services, and needlessly introduce increased risk of right of way and other public safety hazards.”On Tuesday, Seattle announced plans to appeal the decision in federal court.”This is more than just an unfunded mandate, requiring us to do something without paying for the cost,” said Seattle city attorney Pete Holmes. “This is more like a taking, frankly, without due process and without compensation. Cities have property rights, and that has really just been thrown out with this ruling.”He called the deal “a gift to the industry” that will “deny us a return on our assets that we enjoy today.”Fees and processes vary widely from place to place, and are often used to fund other city services. Holmes said that companies in Seattle can pay up to $1,800 per pole as an annual fee; prices go up to $5,100 for prime Manhattan locations and down to $148 in neighborhoods where the city wants to incentivize more deployment, according to Bloomberg.In Los Angeles, the city said that the break-even point for small cell facilities is $800 per installation. But in exchange for amenities such as free Wi-Fi in Skid Row and at recreation centers, $400,000 of scholarship money, and launching an innovation center in the city, L.A. is charging Verizon just $175 per device per year for 10 years for up to 1,000 installations, plus the cost of electricity.Jeanne Holm, L.A.’s deputy chief information officer, said the city cut a good deal: “Verizon brought a bunch of stuff to the table which, in my opinion, is well worth that offset, and our financial analysts have also agreed.”The details of the city’s deal with Verizon are currently in front of the City Council for approval, as are preliminary plans for a mobile 5G deal with AT&T.Although the city’s fee for Verizon is below the maximum set by the FCC, the new rules could give the carrier a chance to renegotiate on terms it considers more favorable.Jonathan LeCompte, president of Verizon’s Pacific market, said he couldn’t speak on the specifics of the Los Angeles deal without the financials in front of him, but said “if it’s a little bigger delta between the numbers, there might be a different plan of attack.”In a letter to the FCC, Mayor Eric Garcetti urged the commission to rewrite the ruling before its adoption, arguing that the decision would “insert confusion into the market, and sow mistrust between my technology team and the carriers with whom we have already reached agreements.”The L.A. city attorney’s office did not respond to requests for comment.Small cell 5G technology relies on higher-frequency radio waves than current wireless services to deliver faster speeds—but at shorter ranges. Those higher-frequency signals, which measure in millimeters, can be obstructed by objects of a similar size, such as leaves and raindrops.Twenty U.S. states have enacted legislation that streamlines regulation on 5G small cell installation, and a California bill that would have reduced local power to block new installations was vetoed by Gov. Jerry Brown late last year.The FCC says the new rule will save money for telecommunications companies, which will redirect those funds to deploy 5G service to less-connected rural areas.Industry experts dispute this hypothesis—and leading telecoms say rural areas are not their first priority for 5G service.”No one believes that’s going to happen,” said Levin, the former FCC official. “Inside the Beltway, they say if they save them a buck in New York they’ll go deploy in Montana. That’s not just dumb, that’s a special kind of stupid.”The FCC did not respond to a Times request for comment.Scott Mair, AT&T’s president of operations, said “small cell technology will start initially for mobile networks in dense urban areas and suburban areas.””Rural America will have 5G over time,” he said.LeCompte, of Verizon, said that rural markets are not a part of the company’s initial rollout plan, but added that “obviously, we need to care for those.”LeCompte praised the permitting process in Los Angeles and Sacramento, but said “in general the permitting process and the flow of paperwork is a long pole in the tent on deploying 5G.”The deal between Verizon and Los Angeles has allowed the city to focus on infrastructure in underserved neighborhoods with low broadband access.”For the initial rollout, we agreed that the downtown area made a lot of sense—partly because we knew the convention center would be an early hub, and wanted to reach out to areas like Pico-Union and others that are underserved around USC,” Holm said.She estimated that it would take 8,000 to 10,000 small cells to fully cover the city. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Lampposts around downtown Los Angeles are being wired with fiber optic cable and shoebox-sized gadgets to beam the fifth and fastest generation of cellular data, known as 5G, into homes and mobile devices. City of Seattle fighting federal government’s new 5G rules This high-tech infrastructure build-out is the result of a deal between the city and Verizon—Los Angeles gave the wireless carrier a break on the fees for taking up space on streetlights in exchange for a package of amenities and services.Such arrangements are common nationwide, where local governments have long leveraged access to public property and rights of way as a bargaining chip to accomplish policy goals.But late last month, the Federal Communications Commission took the unusual step of nationalizing public infrastructure for 5G installation, throwing L.A.’s deal with Verizon and agreements between other cities and carriers into question in the process.The FCC established a maximum price that local governments can charge telecom companies for small cell installations on public poles and in city streets: $270. The agency also established what it called a “shot clock” mandating that permits for small cell infrastructure be processed within 60 to 90 days, depending on the type of installation. If the permits take longer, the telecom companies can take cities to court.Cities charging more than the maximum rate of $270 are open to litigation, and according to the ruling will have to prove that the higher fee is a reasonable approximation of costs.”There has never been a federal decision to price-regulate the way local governments provide access to their own property,” said Blair Levin, a fellow at the Brookings Institution who served as chief of staff to the Clinton-era chairman of the FCC. “That’s an extreme step.”FCC Chairman Ajit Pai said the ruling will hasten the rollout of the new technology, which debuted in the homes of some Verizon customers in Los Angeles this week. “Big-city taxes on 5G slow down deployment there and also jeopardize the construction of 5G networks in suburbs and rural America,” he wrote in a statement accompanying the ruling.Local governments across the country, however, say the rules are too friendly to the telecom industry. ©2018 Los Angeles Times Distributed by Tribune Content Agency, LLC. 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A Chinese firm has won the $1.4 billion contract to build a bridge over the Panama Canal The government of Panama awarded Tuesday a Chinese consortium a $1.4 billion contract to build a bridge over the Panama Canal, a day after a visit by President Xi Jinping. That tour was part of China’s efforts to extend its political and economic influence in Latin America.”Panama is moving ahead in its relations with China and without a doubt this project that begins its construction today is part of that message and trust between the two countries,” Panamanian President Juan Carlos Varela said.The order will allow a consortium called Panama Cuarto Puente, composed of China Communications Construction Company (CCCC) and its unit China Harbour Engineering Company (CHEC), to design and build a bridge over the Panama Canal.The group outbid companies from Spain, Italy, South Korea and China.It will be one of the largest construction projects in Panamanian history.During his visit Xi and Varela signed a score of infrastructure, tourism and development cooperation agreements as Panama became the first Latin American country to partner with Beijing’s giant multi-billion dollar “Belt and Road” development initiative. Citation: Panama awards $1.4 bn bridge project to Chinese group (2018, December 5) retrieved 17 July 2019 from https://phys.org/news/2018-12-panama-awards-bn-bridge-chinese.html This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. © 2018 AFP Explore further Smithsonian opens climate change lab in Panama
© 2018 The Associated Press. All rights reserved. Apple is pulling older models of its iPhone from German stores after losing two patent cases brought by chipmaker Qualcomm, the company said Thursday. Citation: Apples pulls iPhone 7, 8 from German stores in patent spat (2018, December 20) retrieved 17 July 2019 from https://phys.org/news/2018-12-apples-iphone-german-patent-spat.html Explore further Apple risks iPhone ban in Germany after court case loss This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Credit: CC0 Public Domain A regional court in Munich ruled that Apple and its subsidiaries had breached a European patent held by San Diego-based Qualcomm, which has pursued similar cases elsewhere around the world.”Qualcomm’s campaign is a desperate attempt to distract from the real issues between our companies,” Apple said in a statement.”Their tactics, in the courts and in their everyday business, are harming innovation and harming consumers,” it said. “Qualcomm insists on charging exorbitant fees based on work they didn’t do and they are being investigated by governments all around the world for their behavior.”Apple said that pending its appeal, the sale of iPhone 7 and 8 models will be halted at the 15 Apple stores in Germany. The company noted, however, that all iPhone models remain available from cellphone carriers and resellers in the country.The Munich court said Apple is “banned from offering or distributing unlicensed” devices that use the disputed patent, which regulates the amount of energy provided to the phones’ telecom chips.Apple said the iPhone X, which was also mentioned in the verdict, has since been replaced by a newer model.The court also ruled that Qualcomm should receive unspecified damages from Apple.It’s the second time this month that Apple has been dinged in a legal case brought by Qualcomm. A Chinese court banned some Apple subsidiaries from selling or importing certain iPhones in China after Qualcomm said they infringed on two patents enabling consumers to format photos and manage phone apps using a touch screen. Apple has asked the Fuzhou Intermediate People’s Court to reconsider the ruling.
Citation: Denver airport drivers get stuck in mud using Google Maps (2019, June 26) retrieved 17 July 2019 from https://phys.org/news/2019-06-denver-airport-drivers-stuck-mud.html Explore further Denver drivers using Google Maps to get to the city’s airport last weekend and trying to avoid a traffic jam were sent on a detour that took them down a narrow, muddy dirt road. Renault-Nissan alliance takes Google Android for a drive Credit: CC0 Public Domain © 2019 The Associated Press. All rights reserved. Connie Monsees told KMGH-TV there were about 100 cars on Sunday lined up on the road.She says some cars got stuck behind others that could not move and that other vehicles could not make it across several deep ditches.Monsees says she used her all-wheel drive vehicle to help two strangers get to the airport.Google told ABC News that it works to provide the best directions but that issues can arise due to factors such as weather and it encourages drivers be attentive and use their best judgment. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
Today it’s almost impossible to find an area in which artificial intelligence is irrelevant, whether in manufacturing, advertising or communications. Many companies use learning and networked AI systems, for example to generate precise demand forecasts and to exactly predict customer behavior. This approach can also be used to adjust regional logistics processes. Healthcare also uses specific AI activities, such as prognosis generation on the basis of structured data. This plays a role for example in image recognition: X-ray images are input into an AI system which then outputs a diagnosis. Proper detection of image content is also crucial to autonomous driving, where traffic signs, trees, pedestrians and cyclists have to be identified with complete accuracy. And this is the crux of the matter: AI systems have to provide absolutely reliable problem-solving strategies in sensitive application areas such as medicinal diagnostics and in security-critical areas. However, in the past is hasn’t been entirely clear how AI systems make decisions. Furthermore, the predictions depend on the quality of the input data. Researchers at the Fraunhofer Institute for Telecommunications, Heinrich Hertz Institute, HHI and Technische Universität Berlin have now developed a technology, Layer-wise Relevance Propagation (LRP), which renders the AI forecasts explainable and in doing so reveals unreliable problem solution strategies. A further development of LRP technology, referred to as Spectral Relevance Analysis (SpRAy), identifies and quantifies a broad spectrum of learned decision-making behaviors and thus identifies undesirable decisions even in enormous datasets.Transparent AI Citation: A look inside neural networks (2019, July 2) retrieved 17 July 2019 from https://phys.org/news/2019-07-neural-networks.html In practice the technology identifies the individual input elements which have been used to make a prediction. Thus for example when an image of a tissue sample is input into an AI system, the influence of each individual pixel is quantified in the classification results. In other words, as well as predicting how “malignant” or “benign” the imaged tissue is, the system also provides information on the basis for this classification. “Not only is the result supposed to be correct, the solution strategy is as well. In the past, AI systems have been treated as black boxes. The systems were trusted to do the right things. With our open-source software, which uses Layer-Wise Relevance Propagation, we’ve succeeded in rendering the solution-finding process of AI systems transparent,” says Dr. Wojciech Samek, head of the “Machine Learning” research group at Fraunhofer HHI. “We’re using LRP to visualize and interpret neural networks and other machine learning models. We use LRP to measure the influence of every input variable in the overall prediction and parse the decisions made by the classifiers,” adds Dr. Klaus-Rob-ert Müller, Professor for Machine Learning at TU Berlin. Clarifying how artificial intelligence systems make choices Unreliable solution strategiesTrusting the results of neural networks necessarily means understanding how they work. According to the research team’s tests, AI systems don’t always apply the best strategies to reach a solution. For example, one well-known AI system classifies images based on context. It allocated photographs to the category “Ship’ when a large amount of water was visible in the picture. It wasn’t solving the actual task of recognizing images of ships, even if in the majority of cases it picked out the right photos. “Many AI algorithms use unreliable strategies and arrive at highly impractical solutions,” says Samek, summarizing the results of the investigations. Explore further More information: Sebastian Lapuschkin et al. Unmasking Clever Hans predictors and assessing what machines really learn, Nature Communications (2019). DOI: 10.1038/s41467-019-08987-4 Provided by Fraunhofer-Gesellschaft Artificial intelligence (AI) is already firmly embedded in our everyday lives and is conquering more and more territory. For example, voice assistants are already an everyday item in many people’s smartphones, cars and homes. Progress in the field of AI is based primarily on the use of neural networks. Mimicking the functionality of the human brain, neural networks link mathematically defined units with one another. But in the past it was not known just how a neural network makes decisions. Researchers at the Fraunhofer Institute for Telecommunications, Heinrich Hertz Institute, HHI and Technische Universität Berlin have developed a technology that reveals the criteria AI systems use when making decisions. The innovative Spectral Relevance Analysis (SpRAy) method based on Layer-wise Relevance Propagation technology provides a first peek inside the “black box.” AI, machine learning and moreArtificial intelligence is concerned with the development of systems that can independently solve problems and act analogously to patterns of human thought and behavior. At present the greatest progress is being made in the area of machine learning, a subfield of AI. Machine learning deals with methods of extracting knowledge from data and independently learning contexts contained in the data. The progress is a result of using artificial neural networks based on connections between mathematical calculation units that in principle imitate the neural structure of the human brain. A subfield of machine learning, deep learning, covers a class of new procedures that make it possible to teach and train complex artificial neural networks. These networks consist of a large number of levels which are linked with one another in many-layered structures. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Here the AI system allocates the image to the correct category based on the copyright banner. Nevertheless, the solution strategy is defective. Credit: Fraunhofer HHI Layer-wise Relevance Propagation provides a look inside the “black box.” Credit: Fraunhofer HHI Journal information: Nature Communications Here the AI system classifies an image as a train because tracks are present. Credit: Fraunhofer HHI The new Spectral-wise Relevance Analysis technology renders visible the criteria used by AI systems when making decisions. Credit: Fraunhofer HHI Watching neural networks thinkThe LRP technology decodes the functionality of neural networks and finds out which characteristic features are used, for example to identify a horse as a horse and not as a donkey or a cow. It identifies the information flowing through the system at each node of the network. This makes it possible to investigate even very deep neural networks.The Fraunhofer HHI and TU Berlin research teams are currently formulating new algorithms for the investigation of further questions in order to make AI systems even more reliable and robust. The project partners have published their research results in the journal Nature Communications.
According to ESPN’s Adrian Wojnarowski and Royce Young, Thunder general manager Sam Presti is working with Paul’s agents to “redirect the nine-time All-Star to a new team” after he was traded from the Houston Rockets for Russell Westbrook. It would be particularly difficult for the Heat, as they are hard-capped after completing a sign-and-trade with the Philadelphia 76ers for Jimmy Butler. The two of them would give the Heat the type of star power they’ve been missing since LeBron James, Dwyane Wade and Chris Bosh left Miami, but could they surround them with the role players they’d need to legitimately make a run, especially if they have to part ways with a Justise Winslow, Bam Adebayo or Tyler Herro?The same question applies to any other team in the market for a point guard, such as the Minnesota Timberwolves, Detroit Pistons or Orlando Magic. As well as he might fit, Paul’s contract could be a deal-breaker for some.The views on this page do not necessarily reflect the views of the NBA or its clubs. Presti: “Getting a player of Chris’ caliber gives us another experienced playmaker and leader, while the additional draft picks continue to allow us to further commit to the long-term vision that we are embarking on for the Thunder.” pic.twitter.com/4mxXM6ilQg- OKC THUNDER (@okcthunder) July 17, 2019The Miami Heat are reportedly one of the teams interested in trading for Paul, although Wojnarowski and Young added that other possibilities are being explored.For whichever team lands Paul, what would they be trading for?The prosAt age 33, Paul averaged 15.6 points per game on 41.9 percent shooting from the field and 35.8 percent from 3-point range. Even though he’s not the All-NBA player he once was, he’s still a versatile scorer who can play with and without the ball in his hands.In addition to still being a solid pick-and-roll scorer, Paul has developed into a big-time isolation scorer on the back end of his career. In his first season with the Rockets, Paul averaged the fourth-most isolation points per game and ranked in the 91st percentile with 1.10 points per possession. While he wasn’t nearly as prolific last season, it didn’t stop him from averaging the fourth-most isolation points per game and ranking in the top half of the league (63rd percentile) in efficiency.Paul has almost certainly peaked as an isolation scorer, but being able to pull-up from 3-point range and midrange at a high rate gives him the tools to get his shot off against mismatches. According to NBA.com, Paul made 34.5 percent of his 3-point pull-ups and 47.9 percent of his 2-point pull-ups last season. He was even better in 2017-18, knocking down 38.1 percent of his 3-point pull-ups and 52.7 percent of his 2-point pull-ups.Paul is still also one of the better passers in the NBA. He averaged 8.2 assists per game last season while rarely turning the ball over.According to NBA Miner, almost half of Paul’s assists on the season led directly to 3-pointers. It helped him create 21.1 points per game for his teammates, putting him behind only Russell Westbrook (26.5) and John Wall (21.2) for the most in the league.If surrounded by the right players – ideally shooters and a big man he can run pick-and-rolls with – Paul is still more than capable of quarterbacking an efficient offence.As for the other side of the floor, most advanced metrics still make Paul out to be a positive defender. He finished near the top of the league in steals and deflections once again last season, and Houston’s defensive rating improved by 7.7 points per 100 possessions with him on the court.Paul has always played bigger than his size. He’s an incredibly smart defender who has some of the quickest hands in the league. The combination helps him defend multiple positions, even some forwards. Whichever team acquires him would likely get better defensively with him, not worse.The consThe concern for Paul is that he’s an undersized point guard who has struggled to stay healthy over the last three seasons and has shown serious signs of decline entering his mid-30s.Last season with the Rockets, Paul posted a Player Efficiency Rating (PER) of 19.7 percent, which was the lowest mark of his career. His True Shooting Percentage wasn’t much better. The only time Paul combined to shoot worse from the field, perimeter and free throw line was back when he was a rookie and sophomore, almost 15 years ago.That doesn’t mean Paul is suddenly a negative on offence. Far from it. But those aren’t the numbers you’d hope to see from someone who is being paid like one of the best players in the entire league. Paul still has three more years remaining on his current contract, with him being owed $38.5 million in 2019-20, $41.4 million in 2020-21 and $44.2 million in 2021-22.The final year of the deal is a player option, but it’s hard to believe Paul won’t pick it up.For perspective, Stephen Curry is the only player currently slated to make more than Paul next season. After that, only Curry and Russell Westbrook will make more in 2020-21, followed by Curry and John Wall in 2021-22.Those figures will make it difficult for any team to trade for Paul and build around him. All the signs are pointing towards him not being good enough anymore to be the No. 1 option on a playoff team, so he’d need to be paired with another star. However, Paul and another star’s contracts could add up to as much as $80 million a year, leaving little room to fill out the rest of the roster. Chris Paul might not be a member of the Oklahoma City Thunder for very long.
In Photos: The Stunning Sea Life ‘Stars’ of ‘Big Pacific’ If this starfish is making your mouth water, you’re not alone. When a photo of Plinthaster dentatus went viral on Twitter last week, pasta-lovers did a double take — the sea star looked just like a piece of ravioli. Originally published on Live Science. In Photos: The Wonders of the Deep Sea Marine Marvels: Spectacular Photos of Sea Creatures starfish out here lookin like a snack https://t.co/H7BPqTWsDwby Taboolaby TaboolaSponsored LinksSponsored LinksPromoted LinksPromoted LinksYou May LikeVikings: Free Online GamePlay this for 1 min and see why everyone is addicted!Vikings: Free Online GameUndohear.comThese German hearing aids are going viralhear.comUndoTruthFinder People Search SubscriptionOne Thing All Liars Have in Common, Brace YourselfTruthFinder People Search SubscriptionUndoGundry MD Total Restore SupplementU.S. Cardiologist: It’s Like a Pressure Wash for Your InsidesGundry MD Total Restore SupplementUndoKelley Blue Book2019 Lexus Vehicles Worth Buying for Their Resale ValueKelley Blue BookUndoLivestlyThe List Of Dog Breeds To Avoid At All CostsLivestlyUndo — XD (@radfag_) July 11, 2019 Headbutting Tiny Worms Are Really, Really LoudThis rapid strike produces a loud ‘pop’ comparable to those made by snapping shrimps, one of the most intense biological sounds measured at sea.Your Recommended PlaylistVolume 0%Press shift question mark to access a list of keyboard shortcutsKeyboard Shortcutsplay/pauseincrease volumedecrease volumeseek forwardsseek backwardstoggle captionstoggle fullscreenmute/unmuteseek to %SPACE↑↓→←cfm0-9接下来播放Why Is It ‘Snowing’ Salt in the Dead Sea?01:53 facebook twitter 发邮件 reddit 链接https://www.livescience.com/65934-ravioli-sea-star.html?jwsource=cl已复制直播00:0000:3500:35 The photo of the starfish, captured on the National Oceanic and Atmospheric Administration’s recent expedition to the deep Atlantic Ocean, propelled the tasty looking echinoderm to fame. But until now, the “ravioli” star (also called the cookie star) was a bit of a nobody. Even though scientists have known of the ravioli star for some time, only recently did the creature get a common (non-Latin) name, Christopher Mah, an invertebrate biologist at the Smithsonian Museum at Natural History, told Live Science. Instead, the starfish was known only by its formal scientific name, P. dentatus. [Photos: See the World’s Cutest Sea Creatures] That’s because until now, people rarely had the chance to observe the starfish in its natural habitat. Most of what scientists know about the ravioli star comes from specimens that were already dead, Mah said. Now, with the advent of remotely operated vehicles like NOAA’s Deep Discoverer, which captured rare footage of ravioli stars, everyone has virtual access to these creatures. It was sometime in the last year that Mah began hearing the names “cookie star” and “ravioli star” bouncing around the internet. “It’s just kind of amusing to me,” Mah said, “[The name] just took off so quickly.” The starfish isn’t new or unusual — it has existed at the depths of the ocean for much longer than its moniker. But the way Twitter is interacting with the ravioli star and other marine wonders is completely novel, Mah said. Just the fact that the internet has bred a new name for these creatures is evidence of a new kind of citizen science, he added. That’s a good thing. “Any kind of connection that I think the public has with natural history, with nature is important,” Mah said. As for the ravioli star, its moment in the spotlight is only just beginning. This is an exciting moment for deep-sea creatures like the pasta doppelganger, Mah said. For the first time, scientists have the chance to study how they interact with their environment — what they eat, how they reproduce and how they navigate their underwater world. On the Deep Discoverer’s most recent dive, for instance, the ROV captured another image of a group of ravioli stars ganging up on a sea sponge (a sea creature with no skeleton and a soft, porous body). Until now, scientists knew virtually nothing about this sea star’s biology. This is the Deep Discoverers seventh dive on an expedition called Windows to the Deep.
SHARE In a screengrab from a CCTV camera with a view of the entrance of the Chundawat house is seen members of the family carrying stools, later used in mass hanging. – PTI More morbid details came out in the mysterious deaths of 11 members of a family in Burari here as CCTV footage showed some members bringing stools and wires that were used for their hanging, even as police recovered 11 diaries that were maintained over a period of 11 years.The content of the diaries matched the way the alleged suicides happened, the police said. The diaries had instructions such as “keep water in a cup. When it will change colour, you will be saved.”The family was not expecting to die and thought that “the earth will shake” and “there will be thunder in the sky”, following which they will be saved. Police said that the fact that were in the 11 diaries maintained over a period of eleven years is a coincidence and it is not in any way related to the deaths of the 11 family members.The footage of a camera installed outside a house opposite the residence of the family showed that the elder daughter-in-law of the house, Savita, along with her daughter, Neetu, could be seen bringing five stools that were later used for the members to be hanged.Neetu could be seen in the footage carrying stools accompanied by her mother. Around 10.15 pm, Dhruv and Shivam, the youngest members of the house, were seen taking electrical wires from the plywood shop. These wires were used by the 10 members of the family for hanging. Ten of the 11 members of the Bhatia family were found hanging from an iron-mesh in the ceiling on Sunday, while the body of 77-year-old Narayan Devi, the head of the family, was lying on the floor in another room of the house.Devi’s daughter Pratibha (57), her two sons Bhavnesh (50) and Lalit Bhatia (45) were also among the deceased. Bhavnesh’s wife Savita (48) and their three children – Meenu (23), Nidhi (25), and Dhruv, aged 15, too were found dead. Lalit Bhatia’s wife Tina (42) and their 15-year-old son Shivam were also among those found dead. Pratibha’s daughter Priyanka (33), who was engaged last month and would have married by the end of this year, was also found hanging. human interest COMMENT Delhi Burari deaths: Murders or suicide pact? SHARE SHARE EMAIL Published on RELATED COMMENTS Family members were seen bringing stools, wires for hanging July 05, 2018 crime, law and justice Delhi Burari deaths: Family may have been suffering from ‘shared psychosis’
Published on SHARE Prime Minister Narendra Modi receives bouquet from the BJP president Amit Shah upon his arrival to attend a thanksgiving ceremony by BJP leaders to its allies at the party headquarters in New Delhi. – Reuters SHARE SHARE EMAIL parties and movements Even before the election results, the ruling BJP was in a celebratory mood on Tuesday with the Prime Minister Narendra Modi and party President Amit Shah organising thanksgiving parties for the Union Cabinet and NDA allies.The ruling party condemned the Opposition for raising concerns over EVM movements and alleged tampering, especially in Uttar Pradesh, and asserted that these were the signals of “frustration at their impending loss”.Union Law Minister Ravi Shankar Prasad took a swipe at the opposition, saying EVMs were fine when Mamata Banerjee, N Chandrababu Naidu and Amarinder Singh won elections, but the machines turn unreliable when it appears that Modi is winning the election.Targets Opposition“EVMs are good when Mamata Banerjee became the Chief Minister of West Bengal twice and Amarinder Singh became the Chief Minister of Punjab. If they win, EVMs are good. But when there is an expectation that we will win, because people of this country want Narendra Modi to be Prime Minister again, then EVMs are unreliable,” Prasad said.He advised the Opposition to “accept their defeat with grace” even though 48 hours were left before the counting of the first vote. The counting of votes is on May 23.Meanwhile, the BJP President welcomed the PM and all members of the Council of Ministers at the party headquarters for a “get together” late in the afternoon.The BJP described the meeting as an occasion to thank ministers for “their service to the nation” ahead of the counting of votes. Union Ministers Rajnath Singh, Nitin Gadkari, Arun Jaitley, JP Nadda and Prakash Javadekar were among the key BJP leaders present at the meeting.A few ministers belonging to BJP’s alliance partners, including Ram Vilas Paswan of the Lok Janshakti Party, Harsimrat Kaur Badal from the Akali Dal and Anupriya Patel of the Apna Dal, were also present.Amit Shah also hosted a dinner in the evening for BJP leaders and their alliance partners.Bihar Chief Minister and Janata Dal (United) President Nitish Kumar also arrived in Delhi for the dinner meeting. BJP COMMENT Elections 2019 May 21, 2019 PM and BJP President host meetings with Cabinet and throw a dinner party for alliance partners two days ahead of counting of votes COMMENTS